Microfluidics systems usually have channel dimensions of several tens to hundreds of microns and handle fluids in small quantities from 1 atto-litre to 1 nano-litre. These microfluidic devices have shown great potential to reduce cost in manufacturing, consumption of reagents, and time of analysis and to increase device efficiency and portability. Among various applications, microfluidic devices which handle small amounts of fluids for medical, biological, and chemistry applications are developing rapidly. The reduction in size, weight, and power consumption improvement in sensitivity and the characteristics of low-cost batch manufacturing of these devices have made the technology very appealing for numerous applications. Microfluidic and micromachines have drawn significant attention since their introduction in the 1990s. The approaches for microfluidic device fabrications are described in terms of low volume production (casting, lamination, laser ablation, 3D printing) and high-volume production (hot embossing, injection moulding, and film or sheet operations). Replications approaches require fabrication of mould or master and we describe different methods of mould manufacture, including mechanical (micro-cutting ultrasonic machining), energy-assisted methods (electrodischarge machining, micro-electrochemical machining, laser ablation, electron beam machining, focused ion beam (FIB) machining), traditional micro-electromechanical systems (MEMS) processes, as well as mould fabrication approaches for curved surfaces. Here, we describe direct and replication approaches for manufacturing of polymer microfluidic devices. ![]() Polymer based microfluidic devices offer particular advantages including those of cost and biocompatibility. For more information regarding our products, contact us today.Microfluidic devices offer the potential to automate a wide variety of chemical and biological operations that are applicable for diagnostic and therapeutic operations with higher efficiency as well as higher repeatability and reproducibility. With over 15 years of experience, you can trust us to provide you with the quality solutions you need. Our products are suitable for a wide variety of applications in the medical and semiconductor industries. Kelly Pneumatics is a leading supplier of custom flow and pressure control solutions-from digital air flow meters to proportional control valves. Aside from traditional benchtop applications, their portability allows them to be used in point-of-care application as well. The small size of microfluidic systems allows them to be easily transported, greatly increasing the number of applications they can be used for. The portability of these highly ordered systems is another advantageous feature they possess. By running multiple circuits at the same time, the amount of time that each experiment takes is greatly reduced, allowing for more efficient processes and increased throughput. This simultaneous processing is possible because of the reduced amount of space that each circuit requires. Microfluidic systems allow multiple analytes to be processed at the same time. This increased level of control yields itself to more precise experimentation and accurate results. Microfluidic systems offer an exceptionally high level of control of experimental conditions because of their custom-designed architectures and atomization. ![]() Increased precisionĪnother advantage of microfluidic systems is the increased precision that they offer. ![]() As such, utilizing a microfluidic system can yield significant cost savings by reducing the amount of reagents and samples required for an experiment. However, because microfluidic systems are so small, they consume minimal quantities of these items. Reagents and samples used in biological analysis are often very costly. To learn about some of the main advantages of microfluidic systems, continue reading. ![]() Such devices have a vast variety of applications in many research areas and numerous benefits. Typically, microfluidic systems are just a few hundred microns in size. Microfluidic systems are generally used in controlled biological experiments to facilitate operations that would normally require an entire laboratory in a simple microscopic system. The properties and behavior of the microliter quantities of fluids-which are often much different compared to fluids on a macroscale-are then monitored. Microfluidic systems are nonturbulent, highly miniaturized devices that contain networks of microchannels for fluids to pass through or be contained in.
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